Cursed buttercup Toxic?

Updated 2026-03-06| 4 min read| 4,725 found this helpful
Ranunculus sceleratus L.
1

Toxic protoanemonin forms from non-toxic ranunculin when the plant is wilted, crushed, or damaged

2

Dried plant material and silage stored for 2+ months is non-toxic as protoanemonin breaks down to harmless anemonin

3

Severe poisoning only occurs if large quantities (≥2kg for horses) are ingested acutely or over 3+ weeks

FAQ

Is Cursed buttercup toxic to Humans?

Oral blistering, salivation, gastrointestinal distress (vomiting, diarrhea), hematuria, tremors, and seizures in severe cases of large ingestion (High)

Is Cursed buttercup toxic to Cats?

No species-specific data recorded; expected to cause oral irritation, drooling, vomiting, and diarrhea if ingested (Moderate)

Is Cursed buttercup toxic to Dogs?

No species-specific data recorded; expected to cause oral mucosal irritation, drooling, and gastrointestinal upset if consumed (Moderate)

Is Cursed buttercup toxic to Horses?

Oral blistering, swelling of mouth/lips with excess salivation, diarrhea, colic, hematuria, tremors, seizures, paralysis, rare death from respiratory failure if large amounts are ingested; may cause udder inflammation and discolored bitter milk in lactating mares (High)

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Toxicity Details

Humans
High

Oral blistering, salivation, gastrointestinal distress (vomiting, diarrhea), hematuria, tremors, and seizures in severe cases of large ingestion

Cats
Moderate

No species-specific data recorded; expected to cause oral irritation, drooling, vomiting, and diarrhea if ingested

Dogs
Moderate

No species-specific data recorded; expected to cause oral mucosal irritation, drooling, and gastrointestinal upset if consumed

Horses
High

Oral blistering, swelling of mouth/lips with excess salivation, diarrhea, colic, hematuria, tremors, seizures, paralysis, rare death from respiratory failure if large amounts are ingested; may cause udder inflammation and discolored bitter milk in lactating mares

Toxicity Snapshot

Toxic PartsEntire plant; its sharp, acrid taste usually limits consumption to small non-lethal quantities
Exposure RouteIngestion of fresh or wilted plant material; direct skin contact with damaged plant sap may cause localized irritation
Toxic CompoundsProtoanemonin; Ranunculin

First Aid & Prevention

First 30 Minutes

  • • Remove all remaining plant material from the mouth, skin, or fur of the exposed individual/animal
  • • Rinse the mouth with cool clean water, and wash any exposed skin/fur with mild soap and water
  • • Do not induce vomiting unless directed to do so by a medical or veterinary professional

Contact Vet Immediately

  • • Large quantity of plant is ingested (≥2kg for horses, any measurable amount for small pets)
  • • Symptoms like oral blistering, severe diarrhea, colic, tremors, or seizures are observed
  • • Lactating animals show signs of udder inflammation or produce discolored, bitter milk

Prevention

  • • Avoid grazing livestock in areas with dense Cursed buttercup growth, especially when alternative forage is limited
  • • Ensure silage is stored for a minimum of 2 months before feeding to eliminate all toxic protoanemonin
  • • Keep household pets away from wild or ornamental Cursed buttercup plants in gardens and outdoor areas

Treatment & Prognosis

  • • Perform appropriate decontamination based on exposure route and affected species
  • • Administer mucosal protectants to reduce oral and gastrointestinal irritation
  • • Provide symptomatic supportive care, including antihistamines if needed for severe irritant reactions
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Professional Toxicology

Scientific NameRanunculus sceleratus L.
AliasesCursed crowfoot、Celery-leaved buttercup、Poisonous buttercup
Toxicity Grade
HumansHigh
CatsModerate
DogsModerate
HorsesHigh
Target Organs
Oral mucous membranesGastrointestinal tractKidneysNervous systemRespiratory systemMammary glands (lactating females)
Mechanism of Action

• Intact plants contain non-toxic ranunculin, which is converted to toxic protoanemonin via enzymatic cleavage when the plant is damaged, wilted, or crushed

• Protoanemonin is a strong mucosal and skin irritant; it naturally dimerizes to non-toxic anemonin during drying or extended storage, making processed feed safe

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: Ingestion may cause udder inflammation, as well as discolored, bitter-tasting milk that is unsuitable for consumption
Sheep and goats: Exhibit similar oral and gastrointestinal irritation as other livestock; severe poisoning is rare due to the plant's acrid taste
Confusion Risk

The following plants look similar and may be confused:

Common buttercup Ranunculus acris
Has identical bright yellow flowers, grows in similar habitats; distinguished by its deeply lobed non-celery-shaped leaves, has comparable mild to moderate toxicity
Creeping buttercup Ranunculus repens
Produces the same characteristic buttercup flowers, spreads via creeping stolons; has similar toxicity, distinguished by its lobed hairy leaves
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Larkspur
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Pasqueflower
Pulsatilla vulgaris
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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