Corn buttercup Toxic?

Updated 2026-03-06| 2 min read| 2,093 found this helpful
Ranunculus arvensis L.
1

Toxic protoanemonin forms when the plant is wilted or damaged; fully dried hay and silage aged over 2 months are non-toxic

2

Ingestion of large amounts (2kg for horses) or prolonged exposure over 3 weeks causes severe irritation, neurological symptoms, and rare fatalities

3

All parts of the fresh, undamaged plant contain the non-toxic precursor that converts to poison upon tissue damage

FAQ

Is Corn buttercup toxic to Humans?

No specific human exposure data available; may cause mild skin irritation on contact with damaged plants, and oral/gastrointestinal irritation if ingested (Low)

Is Corn buttercup toxic to Cats?

No species-specific data available; expected to cause mild oral irritation, vomiting and diarrhea if ingested in quantity (Low)

Is Corn buttercup toxic to Dogs?

No species-specific data available; expected to cause mild oral irritation, vomiting and diarrhea if ingested in quantity (Low)

Is Corn buttercup toxic to Horses?

Mild gastroenteritis with small ingestion; 2kg+ ingestion or 3+ weeks of exposure causes blistering, redness/swelling of mouth/lips with salivation, vomiting, diarrhea, colic, weakness, blood in urine, tremors, seizures, paralysis, rare death from respiratory paralysis, and possible udder inflammation with discolored bitter milk in lactating mares (High)

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Toxicity Details

Humans
Low

No specific human exposure data available; may cause mild skin irritation on contact with damaged plants, and oral/gastrointestinal irritation if ingested

Cats
Low

No species-specific data available; expected to cause mild oral irritation, vomiting and diarrhea if ingested in quantity

Dogs
Low

No species-specific data available; expected to cause mild oral irritation, vomiting and diarrhea if ingested in quantity

Horses
High

Mild gastroenteritis with small ingestion; 2kg+ ingestion or 3+ weeks of exposure causes blistering, redness/swelling of mouth/lips with salivation, vomiting, diarrhea, colic, weakness, blood in urine, tremors, seizures, paralysis, rare death from respiratory paralysis, and possible udder inflammation with discolored bitter milk in lactating mares

Toxicity Snapshot

Toxic PartsAll parts of the fresh plant; dry plant material and silage cured for 2+ months are non-toxic
Exposure RouteIngestion of fresh/wilted plant material; direct contact with damaged plant tissue may cause mild skin/mucous membrane irritation
Toxic CompoundsProtoanemonin (toxic irritant); Ranunculin (non-toxic precursor compound); Anemonin (non-toxic stable dimer of protoanemonin)

First Aid & Prevention

First 30 Minutes

  • • Remove all remaining plant material from the animal's mouth and immediate environment
  • • Rinse the oral cavity with cool clean water to reduce mucous membrane irritation
  • • Monitor closely for onset of salivation, blistering, diarrhea or behavioral changes

Contact Vet Immediately

  • • If the animal ingested more than a small handful of fresh/wilted corn buttercup
  • • If symptoms like colic, tremors, difficulty breathing, or blood in urine appear
  • • If a horse ingested 1kg or more of fresh plant material

Prevention

  • • Inspect pastures and fresh forage supplies for corn buttercup growth before grazing/feeding
  • • Ensure silage is cured for a minimum of 2 months before feeding to livestock
  • • Avoid turning out hungry livestock into pastures with heavy Ranunculus infestation

Treatment & Prognosis

  • • Administer decontamination measures as clinically appropriate
  • • Provide mucous membrane protectants to reduce gastrointestinal irritation
  • • Administer antihistamines for inflammatory reactions if indicated
  • • Provide supportive care for neurological or respiratory symptoms as needed
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Professional Toxicology

Scientific NameRanunculus arvensis L.
AliasesDevil-on-all-sides、Scratch bur
Toxicity Grade
HumansLow
CatsLow
DogsLow
HorsesHigh
Target Organs
Oral mucosaGastrointestinal tractKidneysNervous systemRespiratory systemMammary glands (lactating animals)
Mechanism of Action

• Non-toxic ranunculin in intact plant tissue is converted to toxic protoanemonin via enzymatic cleavage when the plant is wilted, crushed or damaged

• Protoanemonin acts as a strong irritant to skin and mucous membranes, and causes neurological damage in high doses

• Protoanemonin rapidly dimerizes to non-toxic anemonin when the plant is fully dried, or fermented in silage for 2+ months

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: Ingestion may cause udder inflammation, red discoloration and bitter taste in milk, plus gastrointestinal and neurological symptoms matching those reported in horses
Small ruminants (sheep, goats): Limited formal data available, expected to develop similar oral and gastrointestinal irritation as horses if large quantities of fresh plant are consumed
Confusion Risk

The following plants look similar and may be confused:

Other buttercup species Ranunculus spp.
Nearly all Ranunculus species have the same toxin profile and similar bright yellow 5-petaled flower morphology, making visual differentiation for non-experts very difficult
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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