Hairy buttercup Toxic?

Updated 2026-03-06| 3 min read| 2,132 found this helpful
Ranunculus sardous Crantz, Ranunculus philonotis Retz
1

Toxic protoanemonin only forms when the plant is wilted or damaged; dried hay containing this plant is non-toxic as protoanemonin converts to harmless anemonin.

2

Small ingestion typically causes only mild gastroenteritis, while large or prolonged intake can lead to severe symptoms including paralysis and rare fatalities in livestock.

3

Silage containing this plant is only safe for feeding after a minimum of 2 months of ensiling, when ranunculin levels drop to non-toxic ranges.

FAQ

Is Hairy buttercup toxic to Humans?

No specific clinical data documented for humans; ingestion is expected to cause mouth and throat irritation, mild abdominal pain, vomiting and diarrhea. (Low)

Is Hairy buttercup toxic to Cats?

No species-specific data available; ingestion may cause oral blistering, excessive salivation, vomiting and diarrhea. (Low)

Is Hairy buttercup toxic to Dogs?

No species-specific data available; ingestion may cause oral blistering, excessive salivation, vomiting and diarrhea. (Low)

Is Hairy buttercup toxic to Horses?

Mild gastroenteritis with small intake; large/extended ingestion causes mouth/lip blisters, redness, swelling and excessive salivation, lower digestive tract irritation leading to diarrhea, colic, weakness, blood in urine, tremors, seizures, paralysis, and rare death from respiratory paralysis; may also cause udder inflammation with reddish, bitter milk in lactating mares. (High)

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Toxicity Details

Humans
Low

No specific clinical data documented for humans; ingestion is expected to cause mouth and throat irritation, mild abdominal pain, vomiting and diarrhea.

Cats
Low

No species-specific data available; ingestion may cause oral blistering, excessive salivation, vomiting and diarrhea.

Dogs
Low

No species-specific data available; ingestion may cause oral blistering, excessive salivation, vomiting and diarrhea.

Horses
High

Mild gastroenteritis with small intake; large/extended ingestion causes mouth/lip blisters, redness, swelling and excessive salivation, lower digestive tract irritation leading to diarrhea, colic, weakness, blood in urine, tremors, seizures, paralysis, and rare death from respiratory paralysis; may also cause udder inflammation with reddish, bitter milk in lactating mares.

Toxicity Snapshot

Toxic PartsEntire plant
Exposure RoutePrimary exposure is ingestion of fresh, wilted or recently damaged plant material; direct skin contact with damaged plant tissue may cause localized irritation and blistering.
Toxic CompoundsProtoanemonin; Ranunculin; Anemonin

First Aid & Prevention

First 30 Minutes

  • • Remove any remaining plant material from the mouth or skin of the exposed individual immediately.
  • • Rinse affected oral cavity or skin with clean, cool water to reduce irritation.
  • • Do not induce vomiting unless explicitly instructed by a medical or veterinary professional.

Contact Vet Immediately

  • • If the exposed animal has ingested more than a small mouthful of fresh/wilted plant material.
  • • If symptoms such as excessive salivation, blistering, diarrhea, colic, tremors or seizures appear post-exposure.
  • • If exposure involves horses or other livestock that may have consumed 1kg or more of the plant.

Prevention

  • • Do not allow pets or livestock to graze in areas with heavy growth of Hairy buttercup.
  • • Ensure silage is ensiled for a minimum of 2 months before feeding to livestock to eliminate toxic ranunculin levels.
  • • Remove all fresh Hairy buttercup plants from animal enclosures; dried plant material is non-toxic and safe in hay.

Treatment & Prognosis

  • • Perform appropriate decontamination procedures based on exposure type.
  • • Administer mucosal protectants to reduce irritation to the digestive tract and oral mucosa.
  • • Provide symptomatic supportive care including fluid therapy for dehydration from diarrhea/vomiting.
  • • Administer antihistamines if required for allergic reactions, and monitor for neurological symptoms (tremors, seizures) closely.
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Professional Toxicology

Scientific NameRanunculus sardous Crantz, Ranunculus philonotis Retz
AliasesSardinian buttercup、Rough buttercup
Toxicity Grade
HumansLow
CatsLow
DogsLow
HorsesHigh
Target Organs
Oral mucosaDigestive tractKidneysNervous systemMammary glands (lactating animals)
Mechanism of Action

• Non-toxic ranunculin in intact plant tissue is converted to toxic protoanemonin via enzymatic cleavage when the plant is wilted or damaged.

• Protoanemonin is a strong irritant that affects mucosal membranes, digestive tract, and nervous system in high doses.

• Protoanemonin is unstable and converts to non-toxic anemonin when dried, making the plant non-toxic in dry hay.

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: Ingestion may cause udder inflammation, with production of reddish, bitter-tasting milk; large intake may cause similar neurological and gastrointestinal symptoms as in horses.
Small ruminants (sheep, goats): Limited data available; expected to cause mild to moderate gastrointestinal irritation if large amounts of fresh plant material are ingested.
Confusion Risk

The following plants look similar and may be confused:

Creeping buttercup Ranunculus repens
Closely related Ranunculus species with similar yellow flowers and hairy foliage; contains the same toxic compounds and has equivalent toxicity profiles.
Meadow buttercup Ranunculus acris
Visually similar with bright yellow 5-petal flowers and lobed leaves; also contains ranunculin and protoanemonin, with matching toxicity risks.
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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