Grape vine Toxic?

Updated 2026-03-06| 4 min read| 1,305 found this helpful
Grape vine
1

Grapes, raisins, currants, sultanas and pomace from Vitis vinifera are highly toxic to dogs, potentially causing fatal acute kidney failure

2

Cats are not highly susceptible to acute kidney injury caused by consumption of Vitis vinifera fruits

3

All plant parts of Vitis vinifera are confirmed to be toxic per published horticultural toxicology literature

FAQ

Is Grape vine toxic to Humans?

No confirmed acute human toxicity data for regular consumption; seek medical attention if adverse reactions occur after large quantity ingestion (Non-toxic)

Is Grape vine toxic to Cats?

No significant acute kidney injury reported, cats are generally not highly susceptible to toxicity from this plant (Low)

Is Grape vine toxic to Dogs?

Within 24 hours: vomiting, diarrhea, lethargy, anorexia; later: polydipsia, polyuria/oliguria/anuria, ataxia, abdominal pain, neurological symptoms, acute kidney failure occurring 24-72 hours post ingestion that can be fatal if untreated. Lab abnormalities include elevated serum creatinine, urea, hypercalcemia, hyperphosphatemia, elevated amylase, and proteinuria (High)

Is Grape vine toxic to Horses?

No available confirmed toxicity data for horses, consult a veterinarian immediately if ingestion occurs (Low)

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Toxicity Details

Humans
Non-toxic

No confirmed acute human toxicity data for regular consumption; seek medical attention if adverse reactions occur after large quantity ingestion

Cats
Low

No significant acute kidney injury reported, cats are generally not highly susceptible to toxicity from this plant

Dogs
High

Within 24 hours: vomiting, diarrhea, lethargy, anorexia; later: polydipsia, polyuria/oliguria/anuria, ataxia, abdominal pain, neurological symptoms, acute kidney failure occurring 24-72 hours post ingestion that can be fatal if untreated. Lab abnormalities include elevated serum creatinine, urea, hypercalcemia, hyperphosphatemia, elevated amylase, and proteinuria

Horses
Low

No available confirmed toxicity data for horses, consult a veterinarian immediately if ingestion occurs

Toxicity Snapshot

Toxic PartsAll plant parts of Vitis vinifera are toxic
Exposure RouteIngestion of any plant parts, especially fresh/dried fruits (grapes, raisins, currants, sultanas) and fruit processing byproducts (pomace)
Toxic CompoundsTartaric acid (2,3-dihydroxysuccinic acid, 2,3-dihydroxybutanedioic acid); Oxalic acid; Potassium bitartrate; Calcium tartrate

First Aid & Prevention

First 30 Minutes

  • • If ingestion occurred within 2 hours and the affected animal is conscious, induce vomiting if safe to do so
  • • Administer activated charcoal to absorb residual toxins
  • • Transport the animal to a veterinary emergency facility immediately

Contact Vet Immediately

  • • If a dog has ingested any amount of grapes, raisins, or any part of the grape vine
  • • If symptoms like vomiting, diarrhea, lethargy, or changes in urination appear after suspected ingestion
  • • If you suspect any pet or livestock has consumed any part of this plant

Prevention

  • • Keep all grape products (fresh grapes, raisins, currants, wine pomace) out of reach of dogs
  • • Do not feed any grape-derived products to dogs
  • • Avoid growing grape vines in areas accessible to unsupervised dogs

Treatment & Prognosis

  • • Decontamination: induce emesis or perform gastric lavage within 12 hours of ingestion
  • • Administer activated charcoal after decontamination to prevent further toxin absorption
  • • Provide intravenous fluid diuresis for a minimum of 48 hours to support renal function
  • • Monitor renal function parameters (serum creatinine, urea, electrolyte levels) for 72 hours post ingestion to detect acute kidney injury early
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Professional Toxicology

Scientific NameVitis vinifera L.
AliasesCommon grape、European grape vine、Wine grape
Toxicity Grade
HumansNon-toxic
CatsLow
DogsHigh
HorsesLow
Target Organs
KidneysGastrointestinal tractNervous system
Mechanism of Action

• Toxicity is linked to high concentrations of dicarboxylic acids (tartaric acid, oxalic acid) present in all plant parts, which cause renal tubular epithelial cell damage leading to acute renal failure in susceptible species (dogs)

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Dog: Highly toxic, ingestion of even small quantities of grapes, raisins, currants, sultanas or pomace can cause fatal acute kidney failure if untreated
Cat: Low risk, cats are not highly susceptible to acute kidney injury caused by consumption of Vitis vinifera fruits, but veterinary consultation is still recommended if large quantities are ingested
Horse: Unknown risk, no confirmed toxicity cases reported, consult a veterinarian immediately if ingestion is suspected
Confusion Risk

The following plants look similar and may be confused:

Other Vitaceae family species Various Vitaceae spp.
Other species in the Vitaceae family are visually similar to Vitis vinifera, sharing characteristic climbing vine growth habit and lobed leaves, and may have similar toxic properties
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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