Mistletoe Toxic?

Updated 2026-03-06| 2 min read| 1,359 found this helpful
Mistletoe
1

The entire mistletoe plant is toxic, containing harmful lectins (including viscumin) and viscotoxin compounds

2

Severe human poisoning only occurs after overdose of parenterally administered mistletoe preparations, not typical oral ingestion

3

Ingestion can cause serious neurological and gastrointestinal symptoms in dogs and horses, with recorded fatalities in dogs and rare deaths in horses

FAQ

Is Mistletoe toxic to Humans?

Gastrointestinal discomfort; severe poisoning (including organ damage) only reported after overdose of injectable unregulated mistletoe products (Low)

Is Mistletoe toxic to Cats?

No specific clinical symptoms documented for cats; monitor for gastrointestinal irritation, lethargy or unusual behavior if ingested (Low)

Is Mistletoe toxic to Dogs?

Salivation, vomiting, diarrhea, increased urination, hypothermia, uncoordinated movement, dilated pupils, heightened sensitivity, muscle twitches, reported fatalities (Moderate)

Is Mistletoe toxic to Horses?

Colic, shortness of breath, poor coordination, rare fatalities (Moderate)

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Toxicity Details

Humans
Low

Gastrointestinal discomfort; severe poisoning (including organ damage) only reported after overdose of injectable unregulated mistletoe products

Cats
Low

No specific clinical symptoms documented for cats; monitor for gastrointestinal irritation, lethargy or unusual behavior if ingested

Dogs
Moderate

Salivation, vomiting, diarrhea, increased urination, hypothermia, uncoordinated movement, dilated pupils, heightened sensitivity, muscle twitches, reported fatalities

Horses
Moderate

Colic, shortness of breath, poor coordination, rare fatalities

Toxicity Snapshot

Toxic PartsEntire plant
Exposure RouteIngestion (primary accidental exposure route), parenteral injection (linked to unregulated therapeutic mistletoe products)
Toxic CompoundsMistletoe lectins (ML I/Viscumin, ML II, ML III); Viscotoxins (A-2, A-3, B, C1)

First Aid & Prevention

First 30 Minutes

  • • Remove any remaining plant material from the mouth of the exposed individual/animal to prevent further ingestion
  • • Induce vomiting only if ingestion occurred within the last 2 hours and the subject is fully conscious
  • • Collect a sample of the ingested plant to share with medical/veterinary providers for accurate diagnosis

Contact Vet Immediately

  • • If a dog, horse or other pet/livestock has ingested any quantity of mistletoe
  • • If you observe abnormal symptoms including uncoordinated movement, breathing difficulty or persistent vomiting after ingestion
  • • If an individual has received an unregulated injectable mistletoe product and shows adverse reactions

Prevention

  • • Keep decorative mistletoe items out of reach of children, pets and livestock
  • • Avoid using unapproved injectable mistletoe therapeutic products not cleared by regulatory authorities
  • • Clearly label mistletoe decorative pieces as toxic to prevent accidental ingestion

Treatment & Prognosis

  • • Administer decontamination measures including activated charcoal or gastric lavage to reduce toxic compound absorption
  • • Provide symptomatic supportive care including fluid therapy, temperature regulation and neurological symptom control as needed
  • • Monitor organ function for 24-48 hours post-exposure to catch delayed adverse effects
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Professional Toxicology

Scientific NameViscum album L.s.l.
AliasesEuropean mistletoe、Common mistletoe、White mistletoe、Wood of the Sacred Cross
Toxicity Grade
HumansLow
CatsLow
DogsModerate
HorsesModerate
Target Organs
Gastrointestinal tractKidneysNervous systemRespiratory systemCardiovascular system
Mechanism of Action

• Lectins (including viscumin) inhibit cellular protein synthesis, leading to cell death and tissue damage

• Viscotoxins disrupt cell membrane function, causing irritation, inflammation and organ dysfunction

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: No formal toxicity data available; monitor for gastrointestinal distress and neurological symptoms if large quantities are ingested
Sheep: No reported poisoning cases; suspected low toxicity for small ingestions
Confusion Risk

The following plants look similar and may be confused:

American Mistletoe Phoradendron leucarpum
Visually similar with evergreen leaves and white berries, grows as a tree parasite; key difference is it is native to North America, with slightly higher toxicity reported in some variants
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Related Toxic Plants

American Mistletoe
American Mistletoe
Phoradendron leucarpum
Moderate toxicity
Australian Mistletoe
Amyema miquelii
Low to Moderate toxicity
Mahogany Mistletoe
Phoradendron rubrum
Moderate toxicity

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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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