Viper's Bugloss Toxic?

Updated 2026-03-06| 3 min read| 4,554 found this helpful
Viper's Bugloss
1

Contains toxic pyrrolizidine alkaloids that cause irreversible liver damage in equines

2

Poisoning most often occurs when horses eat contaminated hay or have no other forage options

3

Symptoms may appear suddenly after an asymptomatic period, progressing rapidly over 1 to 7 days

FAQ

Is Viper's Bugloss toxic to Humans?

No specific toxicity data available for humans; pyrrolizidine alkaloids generally cause liver damage if consumed in large, repeated quantities (Low)

Is Viper's Bugloss toxic to Cats?

Toxicity status is unknown, no documented clinical signs reported to date (Unknown)

Is Viper's Bugloss toxic to Dogs?

Toxicity status is unknown, no documented clinical signs reported to date (Unknown)

Is Viper's Bugloss toxic to Horses?

Weight loss, weakness, lethargy, yawning, incoordination, icterus (yellow mucous membranes), aimless walking, involuntary chewing motions, head pressing, sudden onset of severe symptoms progressing to liver failure (High)

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Toxicity Details

Humans
Low

No specific toxicity data available for humans; pyrrolizidine alkaloids generally cause liver damage if consumed in large, repeated quantities

Cats
Unknown

Toxicity status is unknown, no documented clinical signs reported to date

Dogs
Unknown

Toxicity status is unknown, no documented clinical signs reported to date

Horses
High

Weight loss, weakness, lethargy, yawning, incoordination, icterus (yellow mucous membranes), aimless walking, involuntary chewing motions, head pressing, sudden onset of severe symptoms progressing to liver failure

Toxicity Snapshot

Toxic PartsAll aerial plant parts, including fresh green material and dried plant matter present in contaminated hay
Exposure RouteIngestion of fresh plant material or dried contaminated hay
Toxic CompoundsPyrrolizidine alkaloids

First Aid & Prevention

First 30 Minutes

  • • Immediately remove all access to suspected Echium plantagineum or contaminated hay
  • • Do not induce vomiting unless explicitly directed by a licensed veterinarian
  • • Collect a sample of the ingested plant to aid accurate identification for targeted treatment

Contact Vet Immediately

  • • If your horse has known or suspected exposure to the plant
  • • If any clinical signs like weakness, incoordination, jaundice or abnormal behavior appear post-exposure
  • • If large amounts of the plant are found in your horse's pasture or hay supply

Prevention

  • • Regularly inspect pastures and hay stocks for presence of Viper's Bugloss/Patterson's Curse
  • • Ensure horses have constant access to high-quality forage to avoid eating unpalatable toxic plants
  • • Fully remove all identified plants from grazing areas, including root systems to prevent regrowth

Treatment & Prognosis

  • • Veterinarian-administered supportive care including IV fluids to support liver function
  • • Symptomatic management of neurological complications and liver failure symptoms
  • • Long-term dietary adjustment to reduce liver workload post-exposure
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Professional Toxicology

Scientific NameEchium plantagineum
AliasesPatterson's Curse
Toxicity Grade
HumansLow
CatsUnknown
DogsUnknown
HorsesHigh
Target Organs
LiverCentral nervous system
Mechanism of Action

• Pyrrolizidine alkaloids are metabolized in the liver into toxic intermediates that destroy liver cells, leading to progressive irreversible liver failure and secondary neurological damage

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: Susceptible to pyrrolizidine alkaloid poisoning, developing similar liver failure symptoms as horses post-ingestion
Sheep: More resistant to toxins than horses, but long-term repeated ingestion can cause chronic liver damage
Goats: Similar resistance to sheep, with low risk of acute poisoning but possible chronic liver damage with consistent exposure
Confusion Risk

The following plants look similar and may be confused:

Common Viper's Bugloss Echium vulgare
Visually highly similar with purple-blue spiky inflorescences; E. vulgare has narrower leaves and smaller flowers, and also contains toxic pyrrolizidine alkaloids
Borage Borago officinalis
Shares hairy leaf structure and Boraginaceae family; borage has distinct star-shaped bright blue flowers and much lower pyrrolizidine alkaloid content
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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