Yellow Oleander Toxic?

Updated 2026-03-06| 5 min read| 1,611 found this helpful
Thevetia peruviana
1

All parts of the plant are toxic, with seeds containing the highest concentration of cardiac glycosides at ~5% by weight.

2

Exposure causes gastrointestinal and cardiac symptoms including vomiting, diarrhea, and slowed heart rate in humans and common domestic animals.

3

It poses a severe fatal toxicity risk to cats, dogs, horses, and birds, and is easily confused with equally toxic common oleander.

FAQ

Is Yellow Oleander toxic to Humans?

Vomiting, diarrhea, slowed heart rate, cardiac arrhythmia, potential fatality in untreated severe cases (Severe)

Is Yellow Oleander toxic to Cats?

Vomiting, diarrhea, reduced heart rate, cardiac distress, lethargy, risk of death without prompt veterinary care (Severe)

Is Yellow Oleander toxic to Dogs?

Vomiting, diarrhea, reduced heart rate, cardiac distress, lethargy, risk of death without prompt veterinary care (Severe)

Is Yellow Oleander toxic to Horses?

Vomiting, diarrhea, reduced heart rate, cardiac arrhythmia, colic, risk of fatal cardiac failure (Severe)

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Toxicity Details

Humans
Severe

Vomiting, diarrhea, slowed heart rate, cardiac arrhythmia, potential fatality in untreated severe cases

Cats
Severe

Vomiting, diarrhea, reduced heart rate, cardiac distress, lethargy, risk of death without prompt veterinary care

Dogs
Severe

Vomiting, diarrhea, reduced heart rate, cardiac distress, lethargy, risk of death without prompt veterinary care

Horses
Severe

Vomiting, diarrhea, reduced heart rate, cardiac arrhythmia, colic, risk of fatal cardiac failure

Toxicity Snapshot

Toxic PartsEntire plant, particularly its sap, bark, and seeds
Exposure RouteIngestion of any plant part; skin or eye contact with sap may cause local irritation
Toxic CompoundsCardenolides (cardiac glycosides); Thevetin B (Cerebrosid); Digitoxigenin; Cannogenin; Peruvosid; Thevetin A

First Aid & Prevention

First 30 Minutes

  • • If ingestion is confirmed and the affected individual is conscious, rinse their mouth thoroughly with clean water to remove residual plant material
  • • Do not induce vomiting or administer any food, drink, or home remedies unless explicitly instructed by a medical or veterinary professional
  • • Collect a sample of the plant for identification to speed up clinical treatment

Contact Vet Immediately

  • • Any confirmed or suspected ingestion of any part of the plant, regardless of the amount consumed
  • • Onset of symptoms including vomiting, diarrhea, lethargy, or irregular heart rate after exposure
  • • Sap contact with eyes, open wounds, or sensitive skin leading to persistent irritation

Prevention

  • • Keep the plant out of reach of children, pets, and livestock, especially horses
  • • Wear disposable gloves and eye protection when pruning or handling the plant to avoid sap exposure
  • • Do not burn plant clippings, as toxic fumes may cause respiratory irritation

Treatment & Prognosis

  • • Administer activated charcoal to bind unabsorbed toxins remaining in the gastrointestinal tract
  • • Provide continuous cardiac monitoring to track and regulate heart rate and rhythm abnormalities
  • • Deliver supportive care including IV fluid therapy and anti-emetics to manage dehydration and vomiting
  • • Administer cardiac glycoside-specific antidotes if clinically indicated for severe cases
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Professional Toxicology

Scientific NameThevetia peruviana
Aliases
Toxicity Grade
HumansSevere
CatsSevere
DogsSevere
HorsesSevere
Target Organs
HeartGastrointestinal tractSkinEyes
Mechanism of Action

• Cardenolide compounds inhibit sodium-potassium ATPase pumps in cardiac muscle cells

• This disruption alters normal cardiac electrical activity, leading to bradycardia (slow heart rate) and arrhythmia

• Toxic compounds also irritate the gastrointestinal lining, causing vomiting and diarrhea

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Birds: Severe toxicity (+++), ingestion of even small amounts of plant material can cause rapid fatal cardiac failure
Confusion Risk

The following plants look similar and may be confused:

Common Oleander Nerium oleander
The two species are visually similar with narrow, leathery leaves and bright clustered flowers; both are severely toxic, with common oleander also containing high levels of cardenolides
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Related Toxic Plants

Common Oleander
Common Oleander
Nerium oleander
Severe toxicity
Desert Rose
Desert Rose
Adenium obesum
Severe toxicity
Madagascar Periwinkle
Madagascar Periwinkle
Catharanthus roseus
Moderate toxicity

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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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