American Mistletoe Toxic?

Updated 2026-03-06| 3 min read| 1,722 found this helpful
Phoradendron flavescens
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American Mistletoe is confirmed toxic to cats, dogs, and horses per ASPCA data

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Its primary toxic compounds include toxalbumins and viscumin lectins (phoratoxins)

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Ingestion can cause gastrointestinal distress, abnormal heart rate, and rare respiratory or blood pressure issues

FAQ

Is American Mistletoe toxic to Humans?

No specific human toxicity data is provided, but ingestion may lead to mild to moderate gastrointestinal upset and rare systemic effects (Low)

Is American Mistletoe toxic to Cats?

Vomiting, diarrhea, low blood pressure (rare), difficulty breathing, low heart rate (Moderate)

Is American Mistletoe toxic to Dogs?

Vomiting, diarrhea, low blood pressure (rare), difficulty breathing, low heart rate (Moderate)

Is American Mistletoe toxic to Horses?

Vomiting, diarrhea, low blood pressure (rare), difficulty breathing, low heart rate (Moderate)

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Toxicity Details

Humans
Low

No specific human toxicity data is provided, but ingestion may lead to mild to moderate gastrointestinal upset and rare systemic effects

Cats
Moderate

Vomiting, diarrhea, low blood pressure (rare), difficulty breathing, low heart rate

Dogs
Moderate

Vomiting, diarrhea, low blood pressure (rare), difficulty breathing, low heart rate

Horses
Moderate

Vomiting, diarrhea, low blood pressure (rare), difficulty breathing, low heart rate

Toxicity Snapshot

Toxic PartsAll plant parts, particularly leaves, stems, and white berries, are considered toxic
Exposure RouteIngestion is the primary exposure route; skin contact may cause mild irritation in sensitive individuals
Toxic CompoundsToxalbumin; Pharatoxin viscumin (Lectins, Phoratoxins)

First Aid & Prevention

First 30 Minutes

  • • Immediately remove any remaining plant material from the exposed animal's mouth
  • • Rinse the mouth thoroughly with clean, lukewarm water to remove residual toxin
  • • Do not induce vomiting unless explicitly instructed by a veterinarian or poison control specialist

Contact Vet Immediately

  • • The animal has ingested any quantity of American Mistletoe
  • • Symptoms including vomiting, diarrhea, difficulty breathing, or abnormal heart rate develop
  • • The animal appears lethargic, disoriented, or unresponsive after exposure

Prevention

  • • Keep American Mistletoe holiday decor or wild plants out of reach of pets, horses, and children
  • • Promptly clean up any fallen leaves or berries from the plant in areas accessible to animals
  • • Label mistletoe decor clearly as toxic to prevent accidental ingestion by household members or visitors

Treatment & Prognosis

  • • Veterinarians may administer activated charcoal to reduce gastrointestinal absorption of toxins
  • • Supportive care including IV fluids and anti-emetics will be provided to manage dehydration and gastrointestinal symptoms
  • • Cardiac and respiratory monitoring will be conducted for severe cases, with targeted interventions for low heart rate or breathing impairment
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Professional Toxicology

Scientific NamePhoradendron flavescens
AliasesAmerican Mistletoe
Toxicity Grade
HumansLow
CatsModerate
DogsModerate
HorsesModerate
Target Organs
Gastrointestinal tractHeartRespiratory system
Mechanism of Action

• Toxalbumins and phoratoxins bind to cell surfaces to disrupt protein synthesis and cause cellular damage

• Toxins irritate the gastrointestinal tract lining, triggering vomiting and diarrhea

• Systemic toxin absorption can impair cardiac and respiratory function in moderate to severe cases

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: Moderate toxicity risk; ingestion may cause gastrointestinal distress, weakness, and potential cardiac effects similar to those seen in horses
Sheep: Low to moderate toxicity risk; large ingestions have been linked to vomiting, diarrhea, and mild lethargy in documented cases
Confusion Risk

The following plants look similar and may be confused:

European Mistletoe Viscum album
Visually identical to American Mistletoe with white berries and parasitic growth habit; belongs to the same Viscaceae family and has nearly identical toxic properties, with no easy visual difference for untrained individuals
Eastern Dwarf Mistletoe Arceuthobium pusillum
Smaller Viscaceae family parasitic plant often confused with juvenile American Mistletoe; grows primarily on coniferous trees instead of deciduous hosts, and carries similar toxicity risks for animals
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Related Toxic Plants

European Mistletoe
European Mistletoe
Viscum album
Moderate
Desert Mistletoe
Phoradendron californicum
Moderate
Fir Mistletoe
Arceuthobium abietinum
Low to Moderate

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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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