Birdsville indigo Toxic?

Updated 2026-03-06| 3 min read| 3,583 found this helpful
Indigofera linnaei Ali
1

Contains toxic indospicine (arginine analog) and 3-nitropropionic acid, with secondary poisoning risk for dogs that eat meat from affected animals

2

Causes progressive Birdsville Disease in horses that can be fatal if exposure continues for 2-4 months after symptom onset

3

Arginine supplementation and symptomatic supportive care are the core evidence-based treatment approaches for affected animals

FAQ

Is Birdsville indigo toxic to Humans?

No confirmed toxicity reports in humans are available in current clinical data (Non-toxic)

Is Birdsville indigo toxic to Cats?

No confirmed toxicity data for cats is available; precautionary avoidance of exposure is advised (Low)

Is Birdsville indigo toxic to Dogs?

Hepatotoxicity (liver damage) occurs via secondary poisoning from consuming meat of animals that ingested the plant (Moderate)

Is Birdsville indigo toxic to Horses?

Anorexia, apathy, ataxia, hindlimb weakness, hoof wear, weight loss, eye discharge, blindness, corneal clouding; symptoms worsen with stress, death may occur 2-4 months post-onset, partial recovery is possible if exposure stops (Moderate)

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Toxicity Details

Humans
Non-toxic

No confirmed toxicity reports in humans are available in current clinical data

Cats
Low

No confirmed toxicity data for cats is available; precautionary avoidance of exposure is advised

Dogs
Moderate

Hepatotoxicity (liver damage) occurs via secondary poisoning from consuming meat of animals that ingested the plant

Horses
Moderate

Anorexia, apathy, ataxia, hindlimb weakness, hoof wear, weight loss, eye discharge, blindness, corneal clouding; symptoms worsen with stress, death may occur 2-4 months post-onset, partial recovery is possible if exposure stops

Toxicity Snapshot

Toxic PartsEntire plant
Exposure RouteIngestion (primary consumption of plant material, secondary ingestion of contaminated animal meat for canines)
Toxic CompoundsIndospicine (arginine-like non-proteinogenic amino acid); 3-Nitropropionic acid (3-NPS, carboxylic acid)

First Aid & Prevention

First 30 Minutes

  • • Immediately remove all access to Birdsville indigo plant material for exposed animals
  • • Perform appropriate gastrointestinal decontamination (emesis, activated charcoal) for recently exposed animals per species guidelines
  • • Administer oral arginine or high-arginine feed (alfalfa hay, flaxseed) if available while awaiting veterinary care

Contact Vet Immediately

  • • Any suspected ingestion of Birdsville indigo by horses, even if no symptoms are present
  • • Dogs that have consumed meat from animals known to have grazed on this plant
  • • Appearance of neurological symptoms, eye abnormalities, or unexplained weight loss in animals with access to the plant

Prevention

  • • Inspect pastures regularly for Birdsville indigo growth and fully remove all identified plants
  • • Never feed meat from livestock or horses exposed to this plant to dogs or other canids
  • • Provide sufficient high-quality, arginine-rich forage to reduce risk of horses grazing toxic plants out of hunger

Treatment & Prognosis

  • • Complete decontamination and symptomatic supportive care per veterinary emergency protocols
  • • Oral arginine supplementation, or high-arginine feed (5kg alfalfa hay/day or 0.75kg flaxseed/day for horses)
  • • Intravenous administration of essential amino acids (DL-methionine and lysine) as prescribed by a veterinarian
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Professional Toxicology

Scientific NameIndigofera linnaei Ali
AliasesIndigofera enneaphylla L.
Toxicity Grade
HumansNon-toxic
CatsLow
DogsModerate
HorsesModerate
Target Organs
LiverCentral nervous systemEyesMusculoskeletal system
Mechanism of Action

• Indospicine acts as an arginine analog to disrupt protein synthesis and cause liver damage

• 3-Nitropropionic acid inhibits cellular energy production via mitochondrial dysfunction

• Indospicine accumulates in the tissue of exposed herbivores, leading to secondary liver toxicity in canids that consume contaminated meat

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Sheep: No confirmed toxicity reported even after intentional consumption of the plant
Cattle: No confirmed toxicity reported even after intentional consumption of the plant
Wild canids: At equal risk of secondary hepatotoxicity as domestic dogs if they consume carcasses of exposed herbivores
Confusion Risk

The following plants look similar and may be confused:

Other Indigofera species Indigofera spp.
Many Indigofera species share similar foliage and growth habits; toxicity varies widely across the genus, so accurate species identification is critical
Pasture indigo Indigofera praticola
Visually nearly identical to Birdsville indigo, but this species is confirmed non-toxic to all livestock
True indigo Indigofera tinctoria
Morphologically similar to Birdsville indigo, this cultivated dye crop is confirmed non-toxic to animals
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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