Indigofera lespedezioides Toxic?

Updated 2026-03-06| 2 min read| 2,145 found this helpful
Indigofera lespedezioides Kunth, Indigofera pascuorum Benth.
1

All parts of the plant are toxic, containing harmful substances indospicine and 3-nitropropionic acid

2

It is toxic to horses, and dogs may suffer secondary poisoning if they eat meat of affected animals

3

Symptoms in horses worsen under stress, death may occur 2-4 months after onset, partial recovery is possible if exposure stops timely

FAQ

Is Indigofera lespedezioides toxic to Humans?

No relevant toxicity data for humans is currently available (Non-toxic)

Is Indigofera lespedezioides toxic to Cats?

No confirmed toxicity data for cats is currently available (Non-toxic)

Is Indigofera lespedezioides toxic to Dogs?

May develop liver damage if eating meat of animals that have ingested this plant (Low)

Is Indigofera lespedezioides toxic to Horses?

Anorexia, apathy, gait disorders, severe ataxia, hindlimb weakness, weight loss, eye discharge, blindness, corneal opacity; symptoms worsen under stress, death may occur 2-4 months after symptom onset (Moderate)

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Toxicity Details

Humans
Non-toxic

No relevant toxicity data for humans is currently available

Cats
Non-toxic

No confirmed toxicity data for cats is currently available

Dogs
Low

May develop liver damage if eating meat of animals that have ingested this plant

Horses
Moderate

Anorexia, apathy, gait disorders, severe ataxia, hindlimb weakness, weight loss, eye discharge, blindness, corneal opacity; symptoms worsen under stress, death may occur 2-4 months after symptom onset

Toxicity Snapshot

Toxic PartsWhole plant
Exposure RouteOral ingestion (direct consumption of the plant, or consumption of meat from animals poisoned by this plant for dogs)
Toxic CompoundsIndospicine; 3-Nitropropionic acid (3-NPS)

First Aid & Prevention

First 30 Minutes

  • • Stop exposure to the plant immediately
  • • If recently ingested, induce vomiting under professional guidance if applicable
  • • Keep the affected animal in a quiet environment to avoid stress

Contact Vet Immediately

  • • The animal shows symptoms like anorexia, weakness, gait disorder, eye discharge or blindness
  • • The dog has eaten meat of animals that may have consumed this plant
  • • Symptoms persist or worsen after stopping exposure to the plant

Prevention

  • • Avoid growing this plant in grazing areas for horses and other livestock
  • • Do not feed meat of animals that may have eaten this plant to dogs
  • • Learn to distinguish this plant from non-toxic Indigofera species to avoid accidental ingestion

Treatment & Prognosis

  • • Carry out decontamination and symptomatic therapy per emergency treatment protocols
  • • Provide oral arginine or arginine-rich supplements, such as 5kg alfalfa hay or 0.75kg flaxseed per day
  • • Administer intravenous essential amino acids including DL-methionine and lysine under veterinary guidance
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Professional Toxicology

Scientific NameIndigofera lespedezioides Kunth, Indigofera pascuorum Benth.
AliasesIndigofera pascuorum Benth.
Toxicity Grade
HumansNon-toxic
CatsNon-toxic
DogsLow
HorsesModerate
Target Organs
LiverNervous systemEyesMusculoskeletal system
Mechanism of Action

• The arginine-like non-proteinogenic amino acid indospicine exerts toxic effects and can cause secondary poisoning

• The toxic carboxylic acid 3-nitropropionic acid is another key toxic component of the plant

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Horse: Highly susceptible, may develop multiple neurological and physical symptoms, death may occur 2-4 months after symptom onset
Dog: May suffer liver damage due to secondary poisoning after eating meat of animals that have ingested this plant
Sheep and Cattle: Confirmed to be non-toxic to these two species, no adverse reactions after ingestion
Confusion Risk

The following plants look similar and may be confused:

Other Indigofera species Indigofera spp.
Most Indigofera species have similar appearance, while this species is toxic and some other species are non-toxic
Indigofera praticola Indigofera praticola
Visually similar to Indigofera lespedezioides, but Indigofera praticola is completely non-toxic
True Indigo Indigofera tinctoria
Similar in appearance to the toxic species, but Indigofera tinctoria is non-toxic and used for indigo dye production
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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