White clover Toxic?

Updated 2026-03-06| 5 min read| 1,917 found this helpful
White clover
1

Generally non-toxic for most species; poisoning only occurs in rare cases tied to intake volume, weather, season, or fungal infestation

2

Fungal infestation with Rhizoctonia leguminicola, Botrytis fabae Sardiña, or Slafractonia causes toxicity, and infested plants have visible black spots

3

Contains phytoestrogens, cyanogenic glycosides, and photosensitizing compounds that trigger adverse effects at high exposure levels

FAQ

Is White clover toxic to Humans?

No confirmed severe human toxicity cases reported in available clinical data; mild digestive upset may occur with very large intake (Non-toxic)

Is White clover toxic to Cats?

No species-specific toxicity symptoms documented; risk is very low, with mild digestive upset possible only after extreme intake of infested material (Low)

Is White clover toxic to Dogs?

No species-specific toxicity symptoms documented; risk is very low, with mild digestive upset possible only after extreme intake of infested material (Low)

Is White clover toxic to Horses?

No specific severe toxicity cases reported; rare risk of mild photosensitivity or digestive upset with intake of large volumes of infested clover (Low)

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Toxicity Details

Humans
Non-toxic

No confirmed severe human toxicity cases reported in available clinical data; mild digestive upset may occur with very large intake

Cats
Low

No species-specific toxicity symptoms documented; risk is very low, with mild digestive upset possible only after extreme intake of infested material

Dogs
Low

No species-specific toxicity symptoms documented; risk is very low, with mild digestive upset possible only after extreme intake of infested material

Horses
Low

No specific severe toxicity cases reported; rare risk of mild photosensitivity or digestive upset with intake of large volumes of infested clover

Toxicity Snapshot

Toxic PartsAll aerial parts are generally safe; only fungi-infested foliage or plant material consumed in extremely excessive volumes poses toxicity risk
Exposure RouteIngestion of contaminated (fungi-infested) or excessively large quantities of plant material
Toxic CompoundsPhytoestrogens (Formononetin, Genistein, Biochanin); Cyanogenic glycosides (Lotaustralin, Linamarin); Photosensitizing substances

First Aid & Prevention

First 30 Minutes

  • • Immediately remove all remaining white clover material from the affected individual's access to prevent further ingestion
  • • If the individual is alert and ingestion occurred within 2 hours, induce vomiting per medical/veterinary guidance to reduce absorption
  • • Move individuals showing signs of skin irritation or photosensitivity to a fully shaded area away from direct sunlight

Contact Vet Immediately

  • • Signs of cyanide poisoning are observed: bright red blood/mucous membranes, difficulty breathing, excessive salivation, uncoordinated movement, or seizures
  • • Livestock exhibit reproductive abnormalities (abnormal heat cycles, reduced milk yield, abortion, low conception rate) after prolonged clover intake
  • • Severe symptoms including collapse, extreme respiratory distress, or loss of consciousness occur after ingestion

Prevention

  • • Inspect clover forage regularly for black spots indicating toxic fungal infestation, and discard all infested batches
  • • Limit white clover proportion in livestock forage mixes to avoid excessive intake of phytoestrogens and cyanogenic glycosides
  • • Restrict access to large clover patches for animals with known photosensitivity or liver impairment during periods of intense sunlight

Treatment & Prognosis

  • • Administer decontamination measures such as activated charcoal to reduce remaining toxin absorption under professional supervision
  • • For confirmed cyanide poisoning: give 1% sodium nitrite (20-25 mg/kg body weight IV) followed by 25% sodium thiosulfate (0.5-1.25 g/kg body weight IV) per veterinary guidance
  • • Provide supportive care: avoid sun exposure for photosensitivity cases, and deliver reproductive support for livestock with hyperestrogenism
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Professional Toxicology

Scientific NameTrifolium repens L.s.l.
AliasesDutch clover、Creeping clover、Ladino clover
Toxicity Grade
HumansNon-toxic
CatsLow
DogsLow
HorsesLow
Target Organs
Reproductive systemRespiratory systemLiverSkinNervous system
Mechanism of Action

• Phytoestrogens disrupt reproductive hormone signaling, causing hyperestrogenism in sensitive livestock with prolonged high intake

• Cyanogenic glycosides metabolize to release hydrogen cyanide, which impairs blood oxygen transport leading to cyanosis and organ damage

• Photosensitizing compounds accumulate in skin tissue after liver processing, triggering light-induced skin irritation and damage in ruminants

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: Elevated risk of two syndromes: 1) Hyperestrogenism with 3-week latency, causing abnormal heat behavior, vulva swelling, reduced milk yield, <25% conception rate, abortion, and higher post-birth paralysis risk. 2) Cyanide poisoning, causing appetite loss, incoordination, difficulty breathing, salivation, rapid heart rate, and muscle tremors. Ruminants also face higher hepatogenic photosensitivity risk.
Confusion Risk

The following plants look similar and may be confused:

Red clover Trifolium pratense
Closely related with identical trifoliate leaf structure; distinguished by its red/pink flower heads (vs white flowers of white clover) and higher average phytoestrogen content
Alsike clover Trifolium hybridum
Similar low-growing habit and leaf shape, often found in mixed forage stands; distinguished by pale pink-white bicolored flowers and higher inherent photosensitivity risk
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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