Yellow Sweet Clover Toxic?

Updated 2026-03-06| 3 min read| 4,749 found this helpful
Melilotus officinalis Lam., Melilotus arvensis Wallr.
1

Only plants infested with Aspergillus or Penicillium mold are toxic, as healthy plants only contain non-toxic coumarin derivatives

2

The primary toxin dicumarol is a potent anticoagulant that disrupts normal blood clotting function

3

Vitamin K1 is a confirmed, effective antidote for dicumarol poisoning from this plant

FAQ

Is Yellow Sweet Clover toxic to Humans?

No confirmed poisoning cases reported in available datasets; theoretical risk of abnormal bleeding if large volumes of mold-infested plant are ingested (Low)

Is Yellow Sweet Clover toxic to Cats?

Limited species-specific data available; expected symptoms include unexplained bleeding, lethargy, pale mucous membranes, and weakness if large amounts of moldy plant are eaten (Low)

Is Yellow Sweet Clover toxic to Dogs?

Limited species-specific data available; expected symptoms include unexplained external/internal bleeding, pale gums, fatigue, and abdominal pain if moldy plant is ingested (Low)

Is Yellow Sweet Clover toxic to Horses?

Unexplained bleeding (nose, stool, urine, vagina, foal umbilicus), anemia, pale mucous membranes, weakness, abortion, subcutaneous hematomas, joint swelling/stiffness, colic, neurological signs from hypoxia/intracranial bleeding, rapid breathing/heart rate, potentially fatal outcome without treatment (High)

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Toxicity Details

Humans
Low

No confirmed poisoning cases reported in available datasets; theoretical risk of abnormal bleeding if large volumes of mold-infested plant are ingested

Cats
Low

Limited species-specific data available; expected symptoms include unexplained bleeding, lethargy, pale mucous membranes, and weakness if large amounts of moldy plant are eaten

Dogs
Low

Limited species-specific data available; expected symptoms include unexplained external/internal bleeding, pale gums, fatigue, and abdominal pain if moldy plant is ingested

Horses
High

Unexplained bleeding (nose, stool, urine, vagina, foal umbilicus), anemia, pale mucous membranes, weakness, abortion, subcutaneous hematomas, joint swelling/stiffness, colic, neurological signs from hypoxia/intracranial bleeding, rapid breathing/heart rate, potentially fatal outcome without treatment

Toxicity Snapshot

Toxic PartsWhole plant, only when infested with Aspergillus or Penicillium mold species
Exposure RouteIngestion of mold-contaminated fresh plant, hay, or processed forage containing infested yellow sweet clover
Toxic CompoundsCoumarin (0.3-0.9% in healthy plants); 3,4-Dihydrocoumarin (melilotin); o-Dihydrocoumaric acid (melilotic acid); Hydroxycoumarins; Dicumarol (3,3-methylen-bis-4-hydroxycoumarin, primary toxin formed exclusively in mold-infested plants)

First Aid & Prevention

First 30 Minutes

  • • Immediately remove all access to suspected mold-infested yellow sweet clover or contaminated forage for exposed animals
  • • If ingestion was witnessed within 15 minutes, induce vomiting in dogs/cats only under explicit guidance of a veterinary professional
  • • Collect a sample of the ingested plant/forage for laboratory identification to speed up diagnosis

Contact Vet Immediately

  • • Any confirmed or suspected ingestion of mold-infested yellow sweet clover by pets or livestock
  • • Presence of unexplained bleeding, pale gums, lethargy, or unplanned abortion in animals with access to this plant
  • • Presence of unexplained hematomas, joint stiffness, or colic in horses that consume clover-containing forage

Prevention

  • • Thoroughly inspect all hay, forage, and pasture for visible mold growth before feeding to animals
  • • Properly dry clover hay to <15% moisture before storage to prevent mold colonization
  • • Restrict animal access to damp, overgrown areas with large amounts of wild yellow sweet clover

Treatment & Prognosis

  • • Administer Vitamin K1 as the specific antidote per exact veterinary dosage instructions
  • • Perform whole blood transfusion from a healthy matched animal for severe bleeding or acute anemia cases as directed by a vet
  • • Restrict animal physical activity for 2-4 weeks post-exposure to reduce risk of traumatic bleeding while clotting function recovers
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Professional Toxicology

Scientific NameMelilotus officinalis Lam., Melilotus arvensis Wallr.
AliasesYellow melilot、Ribbed melilot、Common melilot、Echter Honigklee (German)、Gewöhnlicher Steinklee (German)、Mélilot officinal (French)、Mélilot jaune (French)、Meliloto comune (Italian)
Toxicity Grade
HumansLow
CatsLow
DogsLow
HorsesHigh
Target Organs
Blood clotting systemMucous membranesUterusJointsGastrointestinal tractKidneysBrainPericardium (heart sac)Mesentery
Mechanism of Action

• Healthy plants only contain non-toxic coumarin and related precursor compounds

• Aspergillus or Penicillium mold growing on the plant converts coumarin precursors to dicumarol via a multi-step biological process

• Dicumarol inhibits vitamin K-dependent clotting factor synthesis in the liver, leading to complete loss of normal blood clotting function and uncontrolled bleeding

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Cattle: High risk of poisoning from mold-infested hay; symptoms include sweet clover disease, umbilical bleeding in newborn calves, abortion, anemia, and fatal bleeding if untreated
Sheep: Similar susceptibility to cattle; may develop bleeding disorders, anemia, and abortion after consuming mold-infested sweet clover forage
Pigs: Lower susceptibility than ruminants, but may develop abnormal bleeding if fed large volumes of mold-contaminated plant material over extended periods
Confusion Risk

The following plants look similar and may be confused:

Other sweet clover species Other Melilotus spp.
All Melilotus species contain coumarin and carry identical risk of becoming toxic when mold-infested; no reliable visual differentiation exists between low-risk and high-risk plants without mold testing
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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