Hairy indigo Toxic?

Updated 2026-03-06| 3 min read| 1,082 found this helpful
Indigofera hirsuta L.
1

Contains toxic indospicine and 3-nitropropionic acid, with secondary poisoning risk for dogs that eat meat from affected livestock

2

Toxic to horses, causing progressive neurological, ocular, and systemic symptoms that may be fatal 2-4 months after onset

3

The entire plant is toxic; treatment relies on decontamination, arginine supplementation, and symptomatic supportive care

FAQ

Is Hairy indigo toxic to Humans?

No confirmed human toxicity data available per provided records (Unknown)

Is Hairy indigo toxic to Cats?

No confirmed cat toxicity data available per provided records (Unknown)

Is Hairy indigo toxic to Dogs?

Hepatotoxicity if consuming meat or liver from livestock that ingested the plant (Low)

Is Hairy indigo toxic to Horses?

Anorexia, apathy, uncoordinated movement/ataxia, hindlimb weakness, weight loss, eye discharge, blindness, corneal clouding; symptoms worsen with stress, partial recovery possible if exposure stops (Moderate)

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Toxicity Details

Humans
Unknown

No confirmed human toxicity data available per provided records

Cats
Unknown

No confirmed cat toxicity data available per provided records

Dogs
Low

Hepatotoxicity if consuming meat or liver from livestock that ingested the plant

Horses
Moderate

Anorexia, apathy, uncoordinated movement/ataxia, hindlimb weakness, weight loss, eye discharge, blindness, corneal clouding; symptoms worsen with stress, partial recovery possible if exposure stops

Toxicity Snapshot

Toxic PartsWhole plant
Exposure RouteIngestion (primary consumption of plant material, secondary consumption of poisoned livestock meat for dogs)
Toxic CompoundsIndospicine (arginine-like non-proteinogenic amino acid); 3-Nitropropionic acid (3-NPS, carboxylic acid)

First Aid & Prevention

First 30 Minutes

  • • Remove all remaining plant material from the affected animal's mouth and block further access to the plant
  • • For recent ingestion, induce vomiting only if explicitly directed by a veterinarian, then administer activated charcoal to reduce toxin absorption
  • • Monitor the animal closely for early signs of appetite loss, unsteady gait, or abnormal behavior

Contact Vet Immediately

  • • Any suspected ingestion of Hairy indigo, especially in horses or dogs that may have eaten meat from exposed livestock
  • • Appearance of symptoms including appetite loss, impaired movement, or eye abnormalities
  • • Symptoms worsen rapidly or the animal shows signs of severe weakness or respiratory distress

Prevention

  • • Avoid grazing horses in pastures infested with Hairy indigo, and ensure all feed supplies are free of the plant
  • • Never feed meat or liver from livestock that may have consumed Hairy indigo to dogs to prevent secondary poisoning
  • • Learn to distinguish toxic Hairy indigo from non-toxic related Indigofera species to avoid accidental exposure

Treatment & Prognosis

  • • Perform decontamination and deliver symptomatic supportive care per standard veterinary emergency protocols
  • • Administer oral arginine or high-arginine supplements (alfalfa hay, flaxseed) as directed by a veterinarian
  • • Provide intravenous essential amino acids (DL-methionine, lysine) under veterinary supervision as required
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Professional Toxicology

Scientific NameIndigofera hirsuta L.
AliasesRoughhairy indigo
Toxicity Grade
HumansUnknown
CatsUnknown
DogsLow
HorsesModerate
Target Organs
LiverNervous systemEyes
Mechanism of Action

• Indospicine acts as an arginine antagonist, disrupting protein synthesis and causing liver damage

• 3-Nitropropionic acid inhibits cellular energy production, leading to neurological impairment

• Indospicine accumulates in the meat and liver of exposed livestock, causing secondary toxicity in dogs that consume these products

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Sheep: No documented toxic effects from consuming Hairy indigo per available research
Cattle: No documented toxic effects from consuming Hairy indigo per available research
General livestock: Consumption leads to indospicine accumulation in meat and liver, creating secondary poisoning risk for canines
Confusion Risk

The following plants look similar and may be confused:

Other Indigofera species Indigofera spp.
Many Indigofera species are visually similar to Hairy indigo, but toxicity varies widely across the genus, so accurate identification is critical
Prairie indigo Indigofera praticola
Visually nearly identical to Hairy indigo, but confirmed non-toxic, leading to high risk of misclassification
True indigo Indigofera tinctoria
Widely cultivated dye plant that closely resembles Hairy indigo, but is confirmed non-toxic to animals
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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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