Eyebright Toxic?

Updated 2026-03-06| 3 min read| 2,943 found this helpful
Euphrasia rostkoviana Hayne s.l.; Euphrasia officinalis L.
1

All parts of the plant are toxic, containing the iridoid glycoside aucubin that disrupts digestive function

2

Ingestion may trigger gastrointestinal inflammation, diarrhea, and colic in humans and animals

3

Prolonged application to dry eyes can worsen keratoconjunctivitis sicca symptoms

FAQ

Is Eyebright toxic to Humans?

Gastrointestinal inflammation, inhibited digestion, diarrhea, colic; prolonged eye application worsens dry eye (keratoconjunctivitis sicca) symptoms (Low)

Is Eyebright toxic to Cats?

No species-specific symptom data available; expected to present gastrointestinal signs including diarrhea and colic if ingested (Low)

Is Eyebright toxic to Dogs?

No species-specific symptom data available; expected to present gastrointestinal signs including diarrhea and colic if ingested (Low)

Is Eyebright toxic to Horses?

No species-specific symptom data available; expected to present gastrointestinal signs including diarrhea and colic if ingested (Low)

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Toxicity Details

Humans
Low

Gastrointestinal inflammation, inhibited digestion, diarrhea, colic; prolonged eye application worsens dry eye (keratoconjunctivitis sicca) symptoms

Cats
Low

No species-specific symptom data available; expected to present gastrointestinal signs including diarrhea and colic if ingested

Dogs
Low

No species-specific symptom data available; expected to present gastrointestinal signs including diarrhea and colic if ingested

Horses
Low

No species-specific symptom data available; expected to present gastrointestinal signs including diarrhea and colic if ingested

Toxicity Snapshot

Toxic PartsWhole plant; also reduces grass growth and forage digestibility for grazing livestock
Exposure RouteOral ingestion of fresh/dried plant material, topical application of eyebright-containing preparations to the eyes
Toxic CompoundsAucubin (Rhinanthin, an iridoid glycoside)

First Aid & Prevention

First 30 Minutes

  • • For ingestion: Induce vomiting only if the affected individual is conscious and alert, within 1 hour of consumption
  • • For eye exposure: Flush eyes gently with clean lukewarm water for 10-15 minutes to remove residual plant matter
  • • Collect remaining plant material for accurate identification to guide follow-up care

Contact Vet Immediately

  • • Ingestion of large quantities of the plant
  • • Persistent diarrhea, colic, or gastrointestinal distress lasting more than 2 hours
  • • Worsening dry eye symptoms after exposure to eyebright preparations

Prevention

  • • Keep eyebright plants and herbal preparations containing eyebright out of reach of children and pets
  • • Avoid prolonged use of eyebright products for dry eye conditions without medical supervision
  • • Inspect grazing pastures regularly to remove eyebright populations to protect livestock

Treatment & Prognosis

  • • Gastrointestinal decontamination via activated charcoal administration for recent large ingestions
  • • Supportive care including fluid therapy to prevent dehydration from diarrhea
  • • Administer prescribed anti-inflammatory and analgesic medications to relieve colic pain
  • • Discontinue use of eyebright eye products and provide appropriate targeted dry eye medications if ocular symptoms worsen
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Professional Toxicology

Scientific NameEuphrasia rostkoviana Hayne s.l.; Euphrasia officinalis L.
AliasesEyewort
Toxicity Grade
HumansLow
CatsLow
DogsLow
HorsesLow
Target Organs
Gastrointestinal tractEyes
Mechanism of Action

• Aucubin irritates the gastrointestinal mucosa, causing inflammation and disrupting normal digestive function

• Unidentified components in topical eyebright preparations exacerbate dry eye symptoms with prolonged use in keratoconjunctivitis sicca cases

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Grazing ruminants (cattle, sheep): Ingestion reduces overall forage digestibility, and large intakes may cause diarrhea and colic, lowering livestock productivity
Confusion Risk

The following plants look similar and may be confused:

Other eyebright species Other Euphrasia spp.
All Euphrasia species are morphologically highly similar, with small white/purple bilabiate flowers and lobed leaves; all share comparable low toxicity profiles
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Related Toxic Plants

Common broomrape
Common broomrape
Orobanche minor
Low to moderate toxicity
Yellow rattle
Yellow rattle
Rhinanthus minor
Low toxicity, causes gastrointestinal upset in grazing animals
Canadian lousewort
Canadian lousewort
Pedicularis canadensis
Low to moderate toxicity, causes neurological signs in high doses

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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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