European spindle Toxic?

Updated 2026-03-06| 5 min read| 3,392 found this helpful
European spindle
1

All plant parts are toxic, with fruits carrying the highest poisoning risk

2

Toxic compounds remain active even in dried hay, posing year-round risk to grazing animals

3

Ingestion in horses can cause fatal outcomes within days of eating even small amounts of branch tips

FAQ

Is European spindle toxic to Humans?

Vomiting, diarrhea, abdominal colic, muscle cramps, circulatory dysfunction (High)

Is European spindle toxic to Cats?

Expected to cause vomiting, diarrhea, abdominal pain, and potential circulatory or neurological symptoms if ingested (High)

Is European spindle toxic to Dogs?

Expected to cause vomiting, diarrhea, abdominal pain, and potential circulatory or neurological symptoms if ingested (High)

Is European spindle toxic to Horses?

Colic, peritonitis, constipation, tachycardia, possible death within several days of ingesting branch tips (High)

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Toxicity Details

Humans
High

Vomiting, diarrhea, abdominal colic, muscle cramps, circulatory dysfunction

Cats
High

Expected to cause vomiting, diarrhea, abdominal pain, and potential circulatory or neurological symptoms if ingested

Dogs
High

Expected to cause vomiting, diarrhea, abdominal pain, and potential circulatory or neurological symptoms if ingested

Horses
High

Colic, peritonitis, constipation, tachycardia, possible death within several days of ingesting branch tips

Toxicity Snapshot

Toxic PartsAll plant parts, particularly the fruits
Exposure RouteIngestion of fresh or dried plant material (including plant matter mixed in hay)
Toxic CompoundsCardenolide-type steroid glycosides (evonoside, evobioside, evomonoside); Evonine (alkaloid); Lectins; Triterpenes

First Aid & Prevention

First 30 Minutes

  • • Induce vomiting only if ingestion occurred <2 hours prior and the affected individual is fully conscious
  • • Administer activated charcoal to absorb unprocessed toxic compounds
  • • Avoid giving food, milk, or other oral supplements unless directed by a medical/veterinary professional

Contact Vet Immediately

  • • If any amount of the plant is ingested by pets, livestock, or young children
  • • If symptoms like repeated vomiting, bloody diarrhea, abnormal heart rate, or severe pain develop
  • • If a horse is suspected of eating any part of the plant, as fatal poisoning is possible

Prevention

  • • Avoid planting European spindle in areas accessible to pets, livestock, or young children
  • • Inspect hay supplies for dried European spindle material before feeding to grazing animals
  • • Educate foragers and property staff to identify and remove wild specimens of the plant

Treatment & Prognosis

  • • Gastrointestinal decontamination via emesis, activated charcoal, or gastric lavage as appropriate
  • • Symptomatic supportive care including fluid therapy, pain management for colic, and cardiovascular support
  • • Continuous monitoring of heart rate, organ function, and gastrointestinal status for at least 72 hours post-exposure
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Professional Toxicology

Scientific NameEuonymus europaeus L.
AliasesSpindle、Common spindle
Toxicity Grade
HumansHigh
CatsHigh
DogsHigh
HorsesHigh
Target Organs
Gastrointestinal tractHeartCentral nervous systemPeritoneum
Mechanism of Action

• Cardenolide glycosides disrupt cardiac sodium-potassium ATPase pumps, leading to circulatory abnormalities

• Alkaloids, lectins and triterpenes cause severe gastrointestinal irritation and tissue inflammation

• Toxic compounds do not degrade when the plant is dried, so hay-contained material remains fully toxic

Other Species Risk (CliniTox)

Information from CliniTox veterinary text.

Sheep: Confirmed poisoning cases reported after ingestion of branches, leaves, and fruits of the plant
Goats: Confirmed poisoning cases reported after ingestion of branches, leaves, and fruits of the plant
Confusion Risk

The following plants look similar and may be confused:

Other Euonymus species Euonymus spp.
Most Euonymus species share highly similar leaf, branch, and fruit morphology; all are considered toxic, so no safe differentiation for consumption is recommended
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Related Toxic Plants

Burning bush
Burning bush
Euonymus alatus
Highly toxic
Oriental bittersweet
Celastrus orbiculatus
Moderately toxic
American bittersweet
Celastrus scandens
Moderately toxic

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Data Sources

This information is for reference only and does not constitute medical advice. If ingestion or poisoning is suspected, seek medical or veterinary attention immediately.

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